HIVdent.org | Oral Manifestations

Last Updated: June 14, 2021

*Featured Articles*
	Longer ART Linked to Clearance of High-Risk HPV in MSM With HIV Natap \| November 14, 2019
	FDA Approves HPV Vaccine For Men And Women Aged 27-45 New York Times \| October 5, 2018
	Top HPV-Associated Cancer Is Now Oropharyngeal August 23,2018
	Human papillomavirus (HPV) and Oropharyngeal Cancer
	Mouth Problems and HIV
	Prevalence of Oral HPV Infection in the United States, 2009-2010
	Improving Access to Oral Health Care for Vulnerable and Underserved Populations
	Genital, Oral, and Anal Human Papillomavirus Infection in Men Who Have Sex with Men
	Oral Ulcers and Necrotizing Gingivitis In Relation to HIV-Associated Neutropenia: A Review and An Illustrative Case NCBI / PubMed \| April 28, 2012
	HPV-associated head and neck cancer: a virus-related cancer epidemic Review NCBI / PubMed \| April 11, 2010
	Oral-Genital Sex & Throat Cancer NATAP \| 09 May 2007
	Oral Manifestations Of HIV/AIDS In The HAART ERA By David A. Reznik, D.D.S. and Christine O’Daniels, RN-BC\|
	HIV Clincian - Special Dental Issue: Implications and Management of Xerostomia in the HIV-Infected Patient Special Dental Issue - March 2005
	A Case-Based Self-Study Module For Dental Health Care Personnel Mountain Plains AIDS Education and Training Center
	Management of Dental Patients Who Are HIV Positive
	Oral Manifestation Of HIV Infection By Drs. Deborah Greenspan and John S. Greenspan

*Research News*
	Checkpoint Inhibition Derails Head and Neck Cancer Progression Dentistry Today \| May 5, 2021
	Use of pritelivir in refractory aciclovir-resistant herpes simplex virus type 2 Int J STD AIDS. 2021 May 4;9564624211006568. doi: 10.1177/09564624211006568.
	The relevance of vitamin D in the oral health of HIV infected patients J Steroid Biochem Mol Biol. 2021 May 4;105905. doi: 10.1016/j.jsbmb.2021.105905
	Malignant ulcer: a great mimicker of gastric plasmablastic lymphoma Clin J Gastroenterol. 2021 Apr 1. doi: 10.1007/s12328-021-01409-3
	Effect of HIV/HAART and Other Clinical Variables on the Oral Mycobiome Using Multivariate Analyses mBio. 2021 Mar 23;12(2):e00294-21. doi: 10.1128/mBio.00294-21.
	Genetic Drivers of Head and Neck Squamous Cell Carcinoma: Aberrant Splicing Events, Mutational Burden, HPV Infection and Future Targets Genes (Basel). 2021 Mar 15;12(3):422. doi: 10.3390/genes12030422
	LiCl Promotes Recovery of Radiation-Induced Oral Mucositis and Dysgeusia Journal of Dental Research \| Mar 11, 2021
	Comparison of salivary total protein and electrolyte profile in HIV patients with and without antiretroviral therapy Dis Mon. 2021 Feb 24;101165. doi: 10.1016/j.disamonth.2021.101165.
	Intra-host changes in Kaposi sarcoma-associated herpesvirus genomes in Ugandan adults with Kaposi sarcoma PLoS Pathog. 2021 Jan 19;17(1):e1008594. doi: 10.1371/journal.ppat.1008594.
	Incidence and duration of incident oropharyngeal gonorrhoea and chlamydia infections among men who have sex with men: prospective cohort study Sex Transm Infect. 2020 Nov 18;sextrans-2020-054764. doi: 10.1136/sextrans-2020-054764
	Mouth pathogens may trigger oral squamous cell carcinoma Dr. Bicuspid \| October 1, 2020
	Are Candida albicans isolates from the oral cavity of HIV-infected patients more virulent than from non-HIV-infected patients? Systematic review and meta-analysis Microb Pathog. 2020 Sep 10;104477. doi: 10.1016/j.micpath.2020.10447
	Oral colonization by Candida species and associated factors in HIV-infected patients in Ahvaz, southwest Iran Epidemiol Health. 2020;42:e2020033. doi: 10.4178/epih.e2020033. Epub 2020 May 24.
	HIV-Associated plasmablastic lymphoma in the era of highly active antiretroviral therapy: a single center experience of 21 patients AIDS. 2020 Jul 21. doi: 10.1097/QAD.0000000000002590
	Transgender Women Have Higher Human Papillomavirus Prevalence Than Men Who Have Sex With Men-Two U.S. Cities, 2012-2014 Sex Transm Dis. 2019 Oct;46(10):657-662. doi: 10.1097/OLQ.0000000000001051
	Immune status, and not HIV infection or exposure, drives the development of the oral microbiota Sci Rep. 2020 Jul 2;10(1):10830. doi: 10.1038/s41598-020-67487-4
	Biofilm-Producing Candida Species Causing Oropharyngeal Candidiasis in HIV Patients Attending Sukraraj Tropical and Infectious Diseases Hospital in Kathmandu, Nepal HIV AIDS (Auckl). 2020 Jun 15;12:211-220. doi: 10.2147/HIV.S255698. eCollection 2020
	Sexual behavior and its association with persistent oral lesions: analysis of the POP-Brazil study Clin Oral Investig. 2020 Jun 25. doi: 10.1007/s00784-020-03407-0
	Concordance between oral and anal human papillomavirus infection in HIV-infected men who have sex with men Oral Dis. 2020 Jan;26(1):224-227. doi: 10.1111/odi.13197
	Alterations in Oral Microbiota in HIV Are Related to Decreased Pulmonary Function Am J Respir Crit Care Med. 2020 Feb 15;201(4):445-457. doi: 10.1164/rccm.201905-1016OC
	Pharyngeal microbiome alterations during Neisseria gonorrhoeae infection PLoS One. 2020 Jan 16;15(1):e0227985. doi: 10.1371/journal.pone.0227985. eCollection 2020
	Factors Associated with Oral Candidiasis in People Living with HIV/AIDS: A Case Control Study Dove Medical Press \| January 14, 2020
	Exploring lay public and dental professional knowledge around HPV transmission via oral sex and ... MD Linx \| November 19, 2019
	Oral Manifestations: Risk Factors for Oral Human Papillomavirus Infection Among Young Men Who Have Sex With Men-2 Cities, United States, 2012-2014 Sex Transm Dis. 2018 Oct;45(10):660-665. doi: 10.1097/OLQ.0000000000000845
	Racial differences in dermatological conditions associated with Human Immunodeficiency Virus: a cross-sectional study of 4,679 patients in an urban tertiary care center J Am Acad Dermatol. 2019 Sep 6. pii: S0190-9622(19)32680-5. doi: 10.1016/j.jaad.2019.08.072
	Transgender Women Have Higher Human Papillomavirus Prevalence Than Men Who Have Sex With Men-Two U.S. Cities, 2012-2014 Sex Transm Dis. 2019 Oct;46(10):657-662. doi: 10.1097/OLQ.0000000000001051
	The Burden of Serious Fungal Infections in Kyrgyzstan J Fungi (Basel). 2019 Jul 19;5(3). pii: E66. doi: 10.3390/jof5030066
	Candida spp. Determination and Th1/Th2 Mixed Cytokine Profile in Oral Samples From HIV+ Patients With Chronic Periodontitis Front Immunol. 2019 Jun 27;10:1465. doi: 10.3389/fimmu.2019.01465. eCollection 2019
	Oral and anal high-risk human papilloma virus infection in HIV-positive men who have sex with men over a 24-month longitudinal study: complexity and vaccine implications BMC Public Health. 2019 May 28;19(1):645. doi: 10.1186/s12889-019-7004-x
	Risk factors, prevalence, and site concordance of human papillomavirus in high-risk Greek men Eur J Cancer Prev. 2018 Sep;27(5):514-520. doi: 10.1097/CEJ.0000000000000366
	Salivary antioxidant and oxidative stress marker levels in HIV-positive individuals Comb Chem High Throughput Screen. 2019 Mar 6.
	Oral manifestations, salivary flow rates and Candida species in Thai HIV-infected patients J Clin Exp Dent. 2019 Feb 1;11(2):e138-e145. doi: 10.4317/jced.55384. eCollection 2019 Feb
	Pre-vaccination prevalence of anogenital and oral human papillomavirus in young HIV-infected men who have sex with men Papillomavirus Res. 2019 Jan 15. pii: S2405-8521(18)30089-2. doi: 10.1016/j.pvr.2019.01.002.
	Oropharyngeal candidiasis in HIV/AIDS patients and non-HIV subjects in the Southeast of Iran Curr Med Mycol. 2018 Dec;4(4):1-6. doi: 10.18502/cmm.4.4.379
	Patterns and trends of HPV-related cancers other than cervix in South Africa from 1994-2013 Cancer Epidemiol. 2018 Dec 14;58:121-129. doi: 10.1016/j.canep.2018.12.004. [Epub ahead of print]
	Ten years of antiretroviral therapy: Incidences, patterns and risk factors of opportunistic infections in an urban Ugandan cohort PLoS One. 2018 Nov 1;13(11):e0206796. doi: 10.1371/journal.pone.0206796. eCollection 2018
	Human papillomavirus prevalence and behavioral risk factors among HIV-infected and HIV-uninfected men who have sex with men in Taiwan Medicine (Baltimore). 2018 Nov;97(45):e13201. doi: 10.1097/MD.0000000000013201
	Risk Factors for Oral Human Papillomavirus Infection Among Young Men Who Have Sex With Men-2 Cities, United States, 2012-2014 Sex Transm Dis. 2018 Oct;45(10):660-665
	Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study BMC Res Notes. 2018 Aug 20;11(1):604. doi: 10.1186/s13104-018-3707-9
	Systematic review of the changing pattern of the oral manifestations of HIV J Investig Clin Dent. 2018 Jul 17:e12351. doi: 10.1111/jicd.12351
	Dysbiosis in the oral bacterial and fungal microbiome of HIV-infected subjects is associated with clinical and immunologic variables of HIV infection PLoS One. 2018 Jul 11;13(7):e0200285. doi: 10.1371/journal.pone.0200285. eCollection 2018
	Oropharyngeal Candidosis in HIV-Infected Patients-An Update Front Microbiol. 2018 May 15;9:980. doi: 10.3389/fmicb.2018.00980. eCollection 2018
	Oral infection by Pseudomonas aeruginosa in patient with chronic kidney disease - a case report J Bras Nefrol. 2018 Apr 19
	Prevalence of current oral HPV infection among 100 betel nut chewers or cigarette smokers in Northern Taiwan J Formos Med Assoc. 2018 Apr 7
	The Burden of Fungal Diseases in Romania J Fungi (Basel). 2018 Mar 1
	Prevalence of anal, oral, penile and urethral Human Papillomavirus in HIV infected and HIV uninfected men who have sex with men J Med Virol. 2018 Feb;90(2):358-366. doi: 10.1002/jmv.24943. Epub 2017 Nov 7
	Prevalence of HIV-related oral manifestations and their association with HAART and CD4+ T cell count: a review J Biol Regul Homeost Agents. 2018 Jan-Feb;32(2 Suppl. 1):51-59.

*News Updates*
	Oral hairy leukoplakia: a series of 45 cases in immunocompetent patients Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Mar 29;4603. doi: 10.1016/j.oooo.2021.03.015.
	Use of pritelivir in refractory aciclovir-resistant herpes simplex virus type 2 Int J STD AIDS. 2021 May 4;9564624211006568. doi: 10.1177/09564624211006568
	HIV Mouth Sores: Types of Sores and Symptoms verywellhealth.com \| March 5, 2021
	How HIV Can Affect the Tongue Verywell Health \| February 27, 2021
	Oral Thrush and HIV: What's the Connection? Healthline \| February 24, 2021
	Oro-facial opportunistic infections and related pathologies in HIV patients: A comprehensive review Dis Mon. 2021 Feb 19;101170. doi: 10.1016/j.disamonth.2021.101170.
	Incidence and survival of HNSCC patients living with HIV compared with HIV-negative HNSCC patients Eur Arch Otorhinolaryngol. 2021 Jan 25. doi: 10.1007/s00405-020-06573-9.
	Caregivers' report of HIV-associated oral manifestations among HIV-unexposed, exposed, and infected Kenyan children Int J Paediatr Dent. 2020 Dec 25. doi: 10.1111/ipd.12771
	The prevalence, risk factors and antifungal sensitivity pattern of oral candidiasis in HIV/AIDS patients in Kumba District Hospital, South West Region, Cameroon Pan Afr Med J. 2020 May 19;36:23. doi: 10.11604/pamj.2020.36.23.18202. eCollection 2020.
	Salivary flow, amylase, and total protein in hospitalized patients with HIV infection / AIDS complications Afr Health Sci. 2020 Jun;20(2):597-604. doi: 10.4314/ahs.v20i2.7.
	A Cross-Sectional Survey to Evaluate Potential for Partnering With School Nurses to Promote Human Papillomavirus Vaccination CDC \| September 24, 2020
	Human Papillomavirus Prevalence in Oral and Oropharyngeal Rinse and Gargle Specimens of Dental Patients and of an HIV-Positive Cohort from Pretoria, South Africa Adv Virol. 2020 Aug 26;2020:2395219. doi: 10.1155/2020/2395219
	Sexual health in dentistry – what you need to look out for Dentistry.co.uk \| July 16, 2020
	Manage Late Effects From HPV-Positive Oropharyngeal Cancers ONS Voice \| June 9, 2020
	Candidiasis and Mechanisms of Antifungal Resistance Antibiotics (Basel). 2020 Jun 9;9(6). pii: E312. doi: 10.3390/antibiotics9060312.
	Signatures of oral microbiome in HIV-infected individuals with oral Kaposi's sarcoma and cell-associated KSHV DNA PLoS Pathog. 2020 Jan 17;16(1):e1008114.
	Do you have white patches in your mouth? Jamaica Observer \| May 3, 2020
	HIV modifies the effect of tobacco smoking on oral human papillomavirus infection MD Linx \| March 27, 2019
	HIV modifies the effect of tobacco smoking on oral human papillomavirus infection J Infect Dis. 2020 Mar 25. pii: jiaa135. doi: 10.1093/infdis/jiaa135
	Oral Health: A Window To Your Overall Health Science Times \| March 2, 2020
	How Marijuana Accelerates Growth of HPV-related Head and Neck Cancer Identified AEGIS \| January 14, 2020
	Tobacco use and oral sex practice among dental clinic attendees PLoS One. 2019 Mar 13;14(3):e0213729. doi: 10.1371/journal.pone.0213729. eCollection 2019
	The burden of oral conditions among adolescents living with HIV at a clinic in Johannesburg, South Africa LoS One. 2019 Oct 16;14(10):e0222568. doi: 10.1371/journal.pone.0222568. eCollection 2019
	Oral Thrush: What Is The Most Effective Treatment For Thrush? Republic World \| September 30, 2019
	More than 70% of US adults are not aware of HPV cancer risks Healio \| September 27, 2019
	Concordance between oral and anal human papillomavirus infection in HIV-infected men who have sex with men Oral Dis. 2019 Sep 17. doi: 10.1111/odi.13197
	Modeling HPV vaccination scale-up among urban young men who have sex with men in the context of HIV NCBI \| May 25, 2019
	The important role dental professionals play in educating patients about HPV prevention Dentistry IQ \| March 22, 2019
	Human immunodeficiency virus and salivary gland pathology: an update Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Jan 9
	Increased risk of tuberculosis in oral cancer patients in an endemic area: a nationwide population-based study Clin Oral Investig. 2019 Feb 28. doi: 10.1007/s00784-019-02864-6
	Pharm To Exam Table – Candida glabrata Urinary Tract Infections University of Nebraska Medical Center \| December 21, 2018 Note from Dr. Reznik – This information is valuable for oral infections with Candida glabrata
	Study links individual HPV types to HIV infection EurekAlert \| October 5, 2018
	FDA Approves HPV Vaccine For Men And Women Aged 27-45 New York Times \| October 5, 2018
	Rising Rates of HPV-Associated Oropharyngeal Cancers: A Challenge For Interprofessional Education and Practice All4OralHealth \| Sept 18, 2018
	Scientists map interactions between head and neck cancer and HPV virus Gladstone Institute \| Sept 12, 2018
	Top HPV-Associated Cancer Is Now Oropharyngeal August 23,2018
	Cetuximab with radiation found to be inferior to standard treatment in HPV-positive oropharyngeal cancer NIH \| August 14, 2018
	John S. Greenspan Papers Update: The Women’s Interagency HIV Study UCSF Archives & Special Collections \| July 31, 2018
	Prevalence of Soft-Tissue Lesions among Women in Sex Work in the Red Light Area of Pune, India: A Cross-Sectional Survey J Int Soc Prev Community Dent. 2018 May-Jun;8(3):218-223. doi: 10.4103/jispcd.JISPCD_46_18
	The effect of subinhibitory concentrations of gentian violet on the germ tube formation by Candida albicans and its adherence to oral epithelial cells Arch Oral Biol. 2017 Oct;82:1-5. doi: 10.1016/j.archoralbio.2017.05.016. Epub 2017 May 25
	The risk of oral tongue cancer in organ transplant recipients and people with HIV
	NIH researchers use genomics to set squamous cell carcinomas apart from other cancers NIH \| April 5, 2018
	Risk factors for oral HPV infection among young men who have sex with men - 2 cities, United States, 2012-2014 Sex Transm Dis. 2018 Apr 5
	Oral HPV Infection Rate Is Alarmingly High in US Men Medscape \| January 25, 2018
	HIV/AIDS in Pakistan Dental News Pakistan \| November 23, 2017
	Oral Cancer Symptoms May Include Difficulty Chewing, Painful Tongue Daily Mail \| November 7, 2017
	Nonavalent HPV Vaccine May Have Protected 77% of HIV+ Men With Anal HPV 16th European AIDS Conference, October 25-27, 2017. Milan
	Extragenital Chlamydia and Gonorrhea in Young Black Men Who Have Sex With Men: Missed Treatment Opportunities for HIV-Infected MSM? Sex Transm Dis. 2017 Oct 19. doi: 10.1097/OLQ.0000000000000746
	Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents AIDSInfo \| October 18, 2017
	Incidence of Herpes Zoster in a Large Cohort of Persons Living with HIV IDWeek2017/IDSA, October 4-8, 2017, San Diego
	Risk for secondary cancers after Kaposi sarcoma has declined Healio \| August 24, 2017

The relevance of vitamin D in the oral health of HIV infected patients

Risk factors, prevalence, and site concordance of human papillomavirus in high-risk Greek men

Oral manifestations, salivary flow rates and Candida species in Thai HIV-infected patients

Oropharyngeal candidiasis in HIV/AIDS patients and non-HIV subjects in the Southeast of Iran

Use of pritelivir in refractory aciclovir-resistant herpes simplex virus type 2

Increased risk of tuberculosis in oral cancer patients in an endemic area: a nationwide population-based study