Oral Microflora Changes in HIV-Infected Patient: A Systematic Review
 

Yuti Malinda1 Yurika Ambar Lita2, Diani Prisinda3,

Department of Oral Microbiology, Faculty of Dentistry, Universitas Padjadjaran, Bandung, West Java, Indonesia.

Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Universitas Padjadjaran, Bandung, West Java, Indonesia.

Department of Conservative Dentistry, Faculty of Dentistry, Universitas Padjadjaran, Bandung, West Java, Indonesia

 

Abstract

Objective: Microbial flora of the oral cavity is extremely diverse. This systematic review evaluated oral microflora in HIV-infected patients that indicated the presence/absence and changes to the microbial condition. The opportunistic infections in HIV are caused by commensal bacteria which are otherwise are harmless in the non-HIV individual.

 

Materials & Methods: A strategic literature search of three databases  (Pubmed, EBSCO, proquest) was conducted from 2009 to 2019. English was accepted as the preferred article language. An abstract and the full text articles were assessed for their relevance with a populations, intervention, comparisons and outcomes (PICO) search strategy using MeSH keywords.

 

Results: Eleven studies fulfilled the criteria set for inclusion "the microbial profile of endodontic infections in HIV-positive and non-HIV subjects". Three studies compared the oral microflora in HIV-positive and HIV-negative subjects whilst eight studies only assessed subjects who were HIV-Positive.

 

Conclusion: This review suggested in some local and systemic conditions, the microfora of the oral cavity changes and that it may be invaded by an increased colonisation of the oral cavity by microbes that are normal commensal of the skin.

 

Keywords: Oral Microflora, Microbial, HIV, Oral Cavity