|Feller L, Khammissa RA, Wood NH, Meyerov R, Pantanowitz
L, Lemmer J
Medunsa Oral Health Centre, Periodontology and Oral Medicine, Pretoria,
Gauteng, South Africa; firstname.lastname@example.org
An unusual case of necrotizing gingivitis and neutropenic
oral ulcers in an HIV-seropositive patient is presented. In spite of a very
low CD4+ T cell count and severe neutropenia, the necrotizing gingivitis
responded favourably to standard periodontal treatment, and the oral ulcers
healed after administration of granulocyte-colony stimulating factor (G-CSF).
Non-specific oral ulcers in HIV-seropositive subjects with neutropenia
should be regarded as neutropenic ulcers. The term non-specific ulcers
should be restricted to those ulcers with non-specific histopathological
features in patients without neutropenia or a nutritional deficiency such as
iron, folic acid and vitamin B.