|Dietz CA, Nyberg CR.
General and HIV Medicine, Kansas City Free Health Clinic, 3515 Broadway St,
Kansas City, MO 64111, USA.
Even though the incidence of anal cancer among men who
have sex with men (MSM) is higher than the incidence of cervical cancer
among women, few MSM are identified as high-risk patients in primary care or
have received vaccination for human papillomavirus (HPV), the most common
sexually transmitted infection worldwide, with 6.2 million new infections
each year. The authors review the current literature on diagnosis and basic
management of genital, oral, and anal HPV infection. Early diagnosis and
treatment of patients with HPV infection is important because this infection
causes patients substantial distress even in its benign manifestations. It
has also been implicated in a host of cancers, including oral, cervical,
penile, and anal cancers and is an independent risk factor for the
development of human immunodeficiency virus infection. The incidence of HPV
infection drops in women older than 30 years but remains high for MSM in all
age ranges. For all of these reasons, physicians should routinely assess the
sexual practices of all male patients, especially MSM, and educate them on
the HPV infection risks,
diagnosis, and treatment options. Physicians can have a
significant impact in the primary prevention of HPV by routinely offering
HPV vaccination to male patients younger than 26 years.